The recent discussion about the half life of L-dopa brings to
mind the following:
I take generic sinemet (25/100) 30 minutes before I eat.
After 30 minutes I can tell that the med is working and I
am "on." I eat after 30 minutes and yet I continue my
on period for 2 1/2 hours. Does the L-dopa get dumped
into the brain all at once and remain there to be "used up"
during the next 2 1/2 hours or does it gradually enter the
brain as it circulates in the bloodstream? If it remainsin
the bloodstream why doesn't the food protein interfer with
it's absorbtion?
If I take the sinemet within an hour AFTER eating it NEVER
seems to work and I remain in an "off" state until about
4-5 hours after eating and then when I take the medicine
it will work within 30 minutes.
