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Bob, thanks for your input. It's good to know we have both "been there-done that" .Looks like I will be sticking with the sinemet. [log in to unmask] ----- Original Message ----- From: Bob Chapman <[log in to unmask]> To: <[log in to unmask]> Sent: Tuesday, September 21, 1999 3:57 AM Subject: Re: Dyskinesias > I can't answer for Merlin, but I can tell you I had the same problem with "very > drowsy and swollen ankles". Over a four month period I took meds to reduce > swellling,didn't work. Had a MRI scan, showed only minor arthritis and > tendentious, Dr. put ankle in a cast for one month, didn't help, Stopped taking > Mirapex (1.5mg per day) and two days later swelling and pain in ankle were gone, > that was about three weeks ago, My tremors are a little worse but I'll take the > swap. I think sinemet is the only med. that is time proven to be the most > effective for the most people. I would think long and hard before giving it up, > but PD and the meds effect us all differently. > > ERVIN J MCCARTHY wrote: > > > Merlin, I have been diagnosed for about two years and have tried Mirapex as > > my first drug and found it to make me very drowsy and swallowen ankles. I > > discontinued Mirapex about two months ago. I have just started Sinemet for > > about three weeks now. I feel at this point my tremors have increased. Is > > this possible? I am beginning to gather from the list that it is a goal to > > get off of sinemet. Is that true? It appears to be in your case. Have you > > had no adverse reactions to Mirapex? Any information would be helpful. > > Thank you > > [log in to unmask] > > ----- Original Message ----- > > From: Merlin H Brown <[log in to unmask]> > > To: <[log in to unmask]> > > Sent: Sunday, September 19, 1999 7:24 PM > > Subject: Re: Dyskinesias > > > > judith, i was taking a 50/200cr at the beginning of the day. then > > sometimes i took 25/100 regular sinemet in the afternoon. my wife says i > > was just starting to exhibit some dyskenesia but i hadn't noticed it. my > > biggest problem with resting tremor on my right side was when i was under > > stress or got very cold. i am now retired and have sold my business so > > the stress is considerably less. yes, i try to minimize my exposure to > > extreme temperatures. i have been taking mirapex for about two years and > > have had no sinemet in that time. the dyskenesia completely disappeared. > > i'm saving the sinemet for a rainy day! lol > > > > murph brown 57/9 > > > > On Sun, 19 Sep 1999 21:37:11 -0400 judith richards <[log in to unmask]> > > writes: > > > Merlin H Brown wrote > > > > > > >nina i take the following > > > >1mg mirapex 3x/day, 5mg selegline 2x/day, 100 mg symetrel 2x/d > > > >by phasing in the mirapex, I was able to completely eliminate the > > > >sinemet. > > > >no dyskinesia. > > > >The preceding provided for what it's worth > > > >murph brown 57/9 > > > > > > Murph, > > > Interesting. How much Sinemet were you taking, how often and for > > > how > > > long, and did you have any dyskinesia before eliminating Sinemet? > > > Thanks, > > > > > > Judith > > > -- > > > Judith Richards, London, Ontario, Canada > > > [log in to unmask] > > > ^^^^ > > > \ / > > > \ | / Today's Research > > > \\ | // ...Tomorrow's Cure > > > \ | / > > > \|/ > > > `````