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Michel, my wife just went thru the Mayo clinic for RLS and she now takes 10/100 sinemet and it seems to help her quite a bit. She takes a sinemet about 7pm and takes her thru the night Good luck. Pat M -----Original Message----- From: Parkinson's Information Exchange [mailto:[log in to unmask]]On Behalf Of Michel Margosis Sent: Wednesday, September 15, 1999 4:09 PM To: [log in to unmask] Subject: Sinemet I just received a call from a dear friend who was diagnosed with sleep apnea and restless leg syndrome, but not PD. Has anyone ever heard of treating RLS with a low dose of Sinemet just for overnight therapy? Michel.