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Michel, my wife just went through the Mayo clinic for RLS and she now takes 10/100 sinemet and it seems to help her quite a bit. She takes a sinemet about 7pm and takes her thru the night This is interesting, I wonder if anyone else takes Sinemet only at nighttime. Is it ever used to improve sleep quality, or just RLS. Lanier Maddux ________________________________________________________ NetZero - We believe in a FREE Internet. Shouldn't you? Get your FREE Internet Access and Email at http://www.netzero.net/download/index.html