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On Sun, 12 Sep 1999 20:01:32 -0700 "J. R. Bruman" <[log in to unmask]> writes: "Because cabergoline seems to have much fewer nasty side effects than bromocriptine, and especially since its half-life of 65 hours permits Parkinson's sufferers to sleep all night through," ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ ^^^^^^^^^^^^^^^^^^^^ Hi from Maine to J.R., Brian, and everyone- Can we please come to a consensus about the meaning of the term, "half-life" ? Knowing what a half-life is could be of IMMENSE help in planning our daily medicaiton routines! I understand it to mean the usual time that elapses from the point that a medication takes effect, until that at which half of the medication has been used up. Am I close? Is this purely based on chem-lab analysis, or also on REAL human beings whose responses to a drug are closely monitored? What are thought to be the half-lives of some of the more convential PD drugs, like sinemet, madopar, sinemet CR, and selegeline? Best regards, Ivan ^^^^^^ WARM GREETINGS FROM ^^^^^^^^^^^^ :-) Ivan Suzman 49/39/36 [log in to unmask] :-) Portland, Maine land of lighthouses 60 deg. F :-) ********************************************************************