Gilles, Thank you for replying. I didn't think there were so many young people with this disease out there, I don't know if I'm happy about that but it helps to know you aren't alone. Thanks for the answers, however grim, five years doesn't seem like much when you are as young as we are. I am taking the Mirapex 3 times a day also and was thrilled to learn of your improvement. I am only taking the .125mg and the doctor is slowly increasing by adding one pill per day every three weeks. I also find the nausea increases with the dosage changes. I am very lucky regarding the cost, I have health insurance which only charges me $5US per months supply. What was the first thing you noticed? My husband noticed that I didn't swing my left arm when we hiked, I thought it was just a left over from a frozen shoulder problem I had. Then I noticed that my left hand couldn't do things that required co-ordination. When I first went to the doctor he told me "I can't find anything wrong with you but your story is pretty good so I will refer you to another doctor" My story! I didn't know I was telling a story. That was in February 99, after five doctors I finally was diagnosed late July 99. "Well I guess you may probably most likely have Parkensons" was what the specialist at San Francisco University told me. Finally in late August I began with the Mirapex. Well that's my pretty good story, did you have one? Sherry