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Bill - I am taking both Mirapex and Permax.  I was introduced to Permax first
(as a supplement to the Sinemet, and instead of an increase in Sinemet
dosage).  I had been suffering from restless legs at night and the Permax was
very helpful.  I titrated up to 1/2 a tablet 3 times a day.

About 18 months later, the leg problem rerturned and this time one Mirapex at
bedtime was added to the regimen.

3 months ago, when it looked like I needed more of something the dosage was
rearranged and currently I take:
    Sinemet (25/100-1/2 tab) and Permax (.5 mg) together 4X/day
    Mirapex (.25 mg) at bedtime
    Eldepryl (5 mg) in A.M.

Everything looks good for now

Nancy Shlaes deGrazia