Paul I will try to answer some of yours questions . IMHO whenever doctors prescribe many different drugs to the same disease it is because they do not know , or have , the right drug .... :-) But I agree with your neuro that up to now the best of them is still levodopa (Sinemet) . Cheers, Paul Lauer wrote: > It seems from the list letters I read that there is no real consensus about > which meds to take. Some start on Sinemet, some on Mirapex, Some on Permax, > some on requip, all with and without Selegiline. Then the game of switching > from one to the other begins along with the associated concerns about the > consequences about switching too early/too late or titrating off or switching > cold and I don't know how many other drugs and permutations are involved > because I'm too new. Is there no school solution? Is it that the neuros are > not privy to it whatever it is? Or is it that people's reactions to the > various drugs are so variable that no global solution has surfaced or been > accepted into the literature. My Neuro started me on Sinemet/Selegiline and > when I asked him why not any of the others, he said that Sinemet was best and > he had stopped prescribing any of the others. > > Paul H. Lauer (PS Carole - I'm in Norwalk and we were pretty lucky with the > storm) -- +----| Joao Paulo de Carvalho |------ + | [log in to unmask] | +--------| Salvador-Bahia-Brazil |------+