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Ervin what i wtite is my opinion only. i believe that sinemet should be withhels as long as possible. am not aware of adding sinemet causing tremors to increase. could be any number of things: adverse reaction to drug. interaction with other drugs; incorrect dosage ,etc. . what dosage of mirapex were you taking? did you phase in the dosages. how long was the phase in period.i had no problems at all with mirapex.i am sure there are many on the board that have had different experiences. that's one of the reasons it's such a frustrating disease look forward to your reply murph brown 57/9 On Mon, 20 Sep 1999 15:43:29 -0700 ERVIN J MCCARTHY <[log in to unmask]> writes: > Merlin, I have been diagnosed for about two years and have tried > Mirapex as > my first drug and found it to make me very drowsy and swallowen > ankles. I > discontinued Mirapex about two months ago. I have just started > Sinemet for > about three weeks now. I feel at this point my tremors have > increased. Is > this possible? I am beginning to gather from the list that it is a > goal to > get off of sinemet. Is that true? It appears to be in your case. > Have you > had no adverse reactions to Mirapex? Any information would be > helpful. > Thank you > [log in to unmask] > ----- Original Message ----- > From: Merlin H Brown <[log in to unmask]> > To: <[log in to unmask]> > Sent: Sunday, September 19, 1999 7:24 PM > Subject: Re: Dyskinesias > > > judith, i was taking a 50/200cr at the beginning of the day. then > sometimes i took 25/100 regular sinemet in the afternoon. my wife > says i > was just starting to exhibit some dyskenesia but i hadn't noticed > it. my > biggest problem with resting tremor on my right side was when i was > under > stress or got very cold. i am now retired and have sold my business > so > the stress is considerably less. yes, i try to minimize my exposure > to > extreme temperatures. i have been taking mirapex for about two > years and > have had no sinemet in that time. the dyskenesia completely > disappeared. > i'm saving the sinemet for a rainy day! lol > > murph brown 57/9 > > On Sun, 19 Sep 1999 21:37:11 -0400 judith richards > <[log in to unmask]> > writes: > > Merlin H Brown wrote > > > > >nina i take the following > > >1mg mirapex 3x/day, 5mg selegline 2x/day, 100 mg symetrel 2x/d > > >by phasing in the mirapex, I was able to completely eliminate the > > >sinemet. > > >no dyskinesia. > > >The preceding provided for what it's worth > > >murph brown 57/9 > > > > Murph, > > Interesting. How much Sinemet were you taking, how often and > for > > how > > long, and did you have any dyskinesia before eliminating Sinemet? > > Thanks, > > > > Judith > > -- > > Judith Richards, London, Ontario, Canada > > [log in to unmask] > > ^^^^ > > \ / > > \ | / Today's Research > > \\ | // ...Tomorrow's Cure > > \ | / > > \|/ > > `````