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Merlin, thanks for the response. I did titrate slowly up to 1.5 mg. When I disgust it with the doctor he stated my complaint was quite common. That's when he started me on sinemet. These were the only two drugs that I have tried although I have been attempting to avoid drugs.Always happy to get another opinion. [log in to unmask] ----- Original Message ----- From: Merlin H Brown <[log in to unmask]> To: <[log in to unmask]> Sent: Monday, September 20, 1999 3:24 PM Subject: Re: Dyskinesias > Ervin > what i wtite is my opinion only. i believe that sinemet should be > withhels as long as possible. am not aware of adding sinemet causing > tremors to increase. could be any number of things: adverse reaction to > drug. interaction with other drugs; incorrect dosage ,etc. . > > what dosage of mirapex were you taking? did you phase in the dosages. > how long was the phase in period.i had no problems at all with mirapex.i > am sure there are many on the board that have had different experiences. > that's one of the reasons it's such a frustrating disease > look forward to your reply > murph brown 57/9 > > > On Mon, 20 Sep 1999 15:43:29 -0700 ERVIN J MCCARTHY > <[log in to unmask]> writes: > > Merlin, I have been diagnosed for about two years and have tried > > Mirapex as > > my first drug and found it to make me very drowsy and swallowen > > ankles. I > > discontinued Mirapex about two months ago. I have just started > > Sinemet for > > about three weeks now. I feel at this point my tremors have > > increased. Is > > this possible? I am beginning to gather from the list that it is a > > goal to > > get off of sinemet. Is that true? It appears to be in your case. > > Have you > > had no adverse reactions to Mirapex? Any information would be > > helpful. > > Thank you > > [log in to unmask] > > ----- Original Message ----- > > From: Merlin H Brown <[log in to unmask]> > > To: <[log in to unmask]> > > Sent: Sunday, September 19, 1999 7:24 PM > > Subject: Re: Dyskinesias > > > > > > judith, i was taking a 50/200cr at the beginning of the day. then > > sometimes i took 25/100 regular sinemet in the afternoon. my wife > > says i > > was just starting to exhibit some dyskenesia but i hadn't noticed > > it. my > > biggest problem with resting tremor on my right side was when i was > > under > > stress or got very cold. i am now retired and have sold my business > > so > > the stress is considerably less. yes, i try to minimize my exposure > > to > > extreme temperatures. i have been taking mirapex for about two > > years and > > have had no sinemet in that time. the dyskenesia completely > > disappeared. > > i'm saving the sinemet for a rainy day! lol > > > > murph brown 57/9 > > > > On Sun, 19 Sep 1999 21:37:11 -0400 judith richards > > <[log in to unmask]> > > writes: > > > Merlin H Brown wrote > > > > > > >nina i take the following > > > >1mg mirapex 3x/day, 5mg selegline 2x/day, 100 mg symetrel 2x/d > > > >by phasing in the mirapex, I was able to completely eliminate the > > > >sinemet. > > > >no dyskinesia. > > > >The preceding provided for what it's worth > > > >murph brown 57/9 > > > > > > Murph, > > > Interesting. How much Sinemet were you taking, how often and > > for > > > how > > > long, and did you have any dyskinesia before eliminating Sinemet? > > > Thanks, > > > > > > Judith > > > -- > > > Judith Richards, London, Ontario, Canada > > > [log in to unmask] > > > ^^^^ > > > \ / > > > \ | / Today's Research > > > \\ | // ...Tomorrow's Cure > > > \ | / > > > \|/ > > > `````