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I have not heard anyone ever express thoughts on the finality of surgical therapy in PD. I am convinced that basic research is by far much more important than surgical centers. Surgery has been proven to be very good palliatives which can last from a few months to a few years and sometimes even longer. SBut, surgery does not cure and the disease still persists, and sometimes when surgery is ineffectual it may even adversely affect the PWP. Pallidotomy changes the characteristics of the brain itself by a careful 'searing' of the pallidum, and once that is done, it is irreversible. When, not if, but When a cure is found, the natural biological synthesis of L-dopamine will be resumed assuming the brain is still functioning in a natural manner. If the alteration of the pallidum interferes with the natural function of the brain, the cure for those who had incurred the pallidotomy may not be available. Emotionally, I can strongly sympathize with those PWP who want relief from the misery of tremors and dyskinesia. Yet, surgery is still only a relief or a reprieve for some. Basic research is the only avenue that can achieve the cure to end the misery of PD. When the cure is found, it will be universal, that is for all PWP, instead of those who can afford temporary relief by surgery. My money and faith is totally in basic research, be it in foetal transplants inter or intra species, recombinant DNA (genetic manipulation), and foremost at this time is the most promising of all is with stem cells. Keep the faith, a cure is coming for sure, and I wish us to be young enough to avail ourselves of it. Michel Margosis