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Michel, your words speak my thoughts! Hilary Michel Margosis wrote: > > I have not heard anyone ever express thoughts on the finality of > surgical therapy in PD. I am convinced that basic research is by far > much more important than surgical centers. Surgery has been proven to > be very good palliatives which can last from a few months to a few > years and sometimes even longer. SBut, surgery does not cure and the > disease still persists, and sometimes when surgery is ineffectual it may > even adversely affect the PWP. > Pallidotomy changes the characteristics of the brain itself by a careful > 'searing' of the pallidum, and once that is done, it is irreversible. > When, not if, but When a cure is found, the natural biological synthesis > of L-dopamine will be resumed assuming the brain is still functioning in > a natural manner. If the alteration of the pallidum interferes with the > natural function of the brain, the cure for those who had incurred the > pallidotomy may not be available. Emotionally, I can strongly > sympathize with those PWP who want relief from the misery of tremors and > dyskinesia. Yet, surgery is still only a relief or a reprieve for some. > > Basic research is the only avenue that can achieve the cure to end the > misery of PD. When the cure is found, it will be universal, that is for > all PWP, instead of those who can afford temporary relief by surgery. > My money and faith is totally in basic research, be it in foetal > transplants inter or intra species, recombinant DNA (genetic > manipulation), and foremost at this time is the most promising of all is > with stem cells. > > Keep the faith, a cure is coming for sure, and I wish us to be young > enough to avail ourselves of it. > > Michel Margosis