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Ronald, I have been using Tasmar for almost a year now and despite the warning and precautions that need to be taken, I think it's done more for me than any single medication and I find it very very valuable. Like your brother, most of the other pd meds have been only marginally successful. I took enough Sinemet ( under doctor's orders) to experience a toxic reaction to it and still did ot have relief from many of my symptoms. Enter Tasmar. It gave the Snippet the boast I needed. I have been relatively stable since I began taking the Tasmar, BTW, I also fight depression most of the time. I haven't any experience with surgery, so I the only comment on that I can make is personally I'm not ready to take that jump yet. I was diagnosed with pd a little over two years ago? It's still all pretty new to me, Assuming you have no liver problems, I would see how the Tasmar works before you try surgery. Good Luck, Cathy 50/48/46 Ronald Erickson wrote: > Hello > Thank you Barbara Patterson and Janet Paterson for the welcome. My name > > is Ron Erickson. My brother has Parkinson D. It began nine years ago. > It is now quite severe. He has had two bad bouts of depression. Most > medications have only been marginally helpful. He has approval now to > use Tasmar. If that is not efficacious he most likely will try a > Pallidotomy. I would appreciate any comments on both the Tasmar and the > > Pallidotomy. Also if anyone has a list of the hospitals and surgeons > that do the operation, that would be helpful. I have a partial list. My > > brother lives in Cando N. Dak.. about a days journey from Minneapolis > (my location). He is considering the University of Minn Hospital for > the surgery, if it comes to that. > Thanks for any info you can give me > Regards, Ron Erickson