Company Press Release Apomorphine: The Rediscovery of an Old Treatment for Parkinson's Disease? - Volunteers Sought for Minneapolis Neuroscience Institute Study MINNEAPOLIS, Sept. 27, 1999 /PRNewswire/ -- Paul Tuite, M.D., of Abbott Northwestern Hospital's Minneapolis Neuroscience Institute, is part of a national team of physicians studying the safety and effectiveness of apomorphine, an investigational medication to control motor fluctuations or varying movements of the arms or legs associated with Parkinson's disease. During the course of the study, examinations, lab tests, evaluations required by the study and medication or placebo will be provided at no cost. At the end of the study, participants may be eligible to receive apomorphine for an additional six months. Apomorphine was discovered in 1869, when doctors combined acid with morphine. The result did not relieve pain nor was it addictive. It was rediscovered in the 1970s and since that time, doctors in France and Britain developed apomorphine tablets that are placed under the tongue. Apomorphine is currently used to treat people with Parkinson's disease in Canada and Europe. It is taken in addition to other anti-parkinsonian medications, such as L-dopa (Sinemet). Study participants must have Parkinson's disease, be between the ages 31 and 75, taking three or more doses of L-dopa (Sinemet) per day, and experience one or more periods of immobility or motor fluctuations per day. The study will require ten visits over 18 weeks. For more information or to participate, call Mary Dargay Richards at 612-863-3200. Abbott Northwestern Hospital is part of Allina Hospitals & Clinics, a non-profit network of hospitals, clinics and other health care services. Allina Hospitals & Clinics provides care throughout Minnesota and western Wisconsin. SOURCE: Allina Health System Copyright © 1999 PRNewswire. -- Judith Richards, London, Ontario, Canada [log in to unmask] ^^^^ \ / \ | / Today’s Research \\ | // ...Tomorrow’s Cure \ | / \|/ `````