Hi Joe: Interested in these alternative delivery systems for levodopa. Can you post some references? Carole H. --- "J. R. Bruman" <[log in to unmask]> wrote: > ARNE KARLSSON wrote: > > My problem is that protein in the food block the > L-dopa uptake from > > the intestines and I have many and deep > OFF-periods during the day. > > Levodopa absorption > Oct 99 > Arne, here are some things I do for the same > problem: > - Try to take levodopa dose when stomach is empty, > along > with plenty of water to ensure it reaches small > intestine > ahead of food. > - Try to confine major protein components to last > meal before > bedtime, and wait a half hour or so for the > stomach to > empty (hopefully) before the evening medication. > - When you can't avoid taking levodopa just before > or just > after eating, don't swallow it immediately but let > it > dissolve partly in your mouth. There is some > absorption > through the mouth lining. > - (ask your doctor first): Levodopa that fails to be > absorbed > in the small intestine just passes through > harmlessly. > Therefore an extra dose occasionally when you're > "off" should > be helpful and not harmful. > - Research is underway for delivering levodopa other > than by > mouth: hypodermic injection; adhesive skin patch; > attached > pump with permanent tube to intestine (available > now). None > of these sounds very attractive to me, but perhaps > when the > PD gets bad enough I'll change my mind. Cheers, > Joe > > -- > J. R. Bruman (818) 789-3694 > 3527 Cody Road > Sherman Oaks, CA 91403-5013 > ===== __________________________________________________ Do You Yahoo!? Bid and sell for free at http://auctions.yahoo.com