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Terry, The PET scan measures the amount of neuro transmitter (i.e.dopamine) activity in the niger striatum These, of course, are the substance of which we PD's are deficient, and one of the key sites in our brains where it occurs. In its capacity to measure bodily processes, in contrast to most imaging techniques which measure bodily structure, the PET scan can be used to diagnose PD but it's very expensive. For any further details, or corrections, I defer to our "resident" medical experts, Charlie and Chris. Msrty Polonsky, Ph.D Clinical Psychologist