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I am 68 and got my PD-diagnos five years ago. Treatment with L-dopa (Madopar) and in addition during the last year Cabergoline (Cabaser) and Tolkapone (Tasmar). My problem is that protein in the food block the L-dopa uptake from the intestines and I have many and deep OFF-periods during the day. In fact main part of day-time. In an attempt to avoid these bad OFF-periods I minimized food containing proteins and instead the energy support was too low. I´ve lost 7 kilograms from 72 to 65 in three months. Now I have contact with a dietist , but the problem resists. I am still 7 kilograms from my ordinary weight. Life is not good when the only thing You can do is sitting and waiting for ON ! If anybody has some good advice please contact the list. Arne