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On Tue 12 Oct, w y wrote: > Hi all, > > Can anyone tell me what is the maximum mg of Sinemet > can be taken up to daily. This is because my mum has > been taking Sinemet but experienced dyskinesia and her > doctor has changed to Madopar which is also another > kind of levodopa but the dosage seems not enough to > cover the six hourly break. And it seems quite hard > for her to tolerate such great pain. Please advise. > > -WENDY- > > ===== > > __________________________________________________ > Do You Yahoo!? > Bid and sell for free at http://auctions.yahoo.com > > > Hello Wendy, You have just dipped your toe into a rather large pool! You are on the right track, and I would like to suggest that you read an article which I wrote specifically to help newcomers like yourself- It's so much easier than writing reams of e-mail every time a newcomer comes along. The web-site containing this note is run by Simon Coles, and is full of interesting Parkinson's-related information. Look for: Living with Levodopa. URL <http://james.parkinsons.org.uk/brian> By the way, to answer your specific questions, I need to know the full details of your mother's present drugs: What tablets, how many, and when taken, plus some detail about your mother: How old, how long since she was diagnosed. First impression is - There is no such thing as a six hour break - To span a 6-hour gap, you would need to take a very large dose of Sinemet or Madopar, which could eat up the margins and cause diskinesias. Don't worry, there are much better ways of achieving the required results with much less strain on your mother. Good luck with the booklet, Regards, -- Brian Collins <[log in to unmask]>