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Sherry, Your reply to my question just proves to me once again how different all us PWP are. I have been taking Mirapex for almost a year now with none of the effects that you have had. I had an STN done in Aug and the 1st week or so I felt much better than I had in years, but that has gone and now I am hoping to duplicate that with the right stimulator settings. I am Happy for you! Marty Rose