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Lenny, The only side affect I have had so far was mostly in the beginning. At first I had nausea all the time, now only once in a while. Then the dizziness when you get up, that was only in the first couple of weeks. The worst was the insomnia. I would only sleep about one or two hours at a time, then have to get up (I wanted to clean house or something! haven't felt like that since I was preggers!). I'm still having some insomnia but heck I wouldn't sleep again if I could always feel this good. Since you have been taking it so long, what long term effects have you seen? I really hope this works more than a short time; have you had good luck? How much do you take? I have only been taking it for four months and only up to a dose of 2.25mg per day, can't wait for more. When do you take yours? I'm thinking of spreading mine out differently so I don't take them so close to bedtime so maybe I could sleep better. What do you think? Sherry