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observing joan during the 20/20 transmission it appeared her morning freezing may be due to under medication. i have successfully dosed at midnight 150 mg of Sinemet CR 100/25 with 1/2 pill artane. while generally i do not believe in sinemet CR due to its unpredictable bonding time with either agonists or inhibitors, the night time dosage seems to be very effective to avoid the consequences faced by joan first thing in the morning fred mann