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Charles T. Meyer, M.D. wrote: > That is a good caveat to note. A difference in bioavailability whether > increased or decreased may occur between "lots" or between generics. With > all generics one should especially watch if the manufacturer changes and be > aware of the possibility of change in efficacy. It is unlikely but it > can happen. Therefore it is best that one insist on the same manufacturer > or watch to see whether a change in symptoms occurs with a change in > generics. This does not mean I am against generics. I support their use. > Just do it with some caution. This is correct. However, performing a bioavailibility test (in vivo) for every batch is far too expensive, so that a more economical (in vitro) Dissolution Test is substituted. All drug store pharmacists have copies of the USP (United States Phamacopeia) where that information is available. Michel