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And how does a medication know where to go in your body. How does the aspirin ( or tylenol) know that whereas yesterday you took it for a headache, today you are taking it for a lower back ache? And most puzzling of all, when you have hemiparkinisonism - how does the sinemet know which side of the body is affected, and why does it not cauae overdose symptoms in the side which is not affected? Hilary Maryse Schild wrote: > > Anyone with a dog knows you dose drugs according to the animal's > weight. Humans usually get the same dosage from age 15 regardless of > size or weight. I always thought it strange. > Maryse