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Rhonda, Let me add my welcome to the List. I concur whole hearrtedly with William's statements. My experience with pd drugs has been fast and harrowing. Diagnosed 2 years ago at the age of 48, I am currently taking 11 25/100 Sinement, 3.0 mg Mirapex, and 400mg Tasmar daily. My nuero was very hesitant to put me on Sinemet so we tried just about everything else before Sinemet. I went through drug after drug and kept declining. I have also seen two pd specialists one who upped the Sinemet and another who concurred with the other doctors. Finally I began to stabilize with a combination of Sinemet and Tasmar. We sere then able to reduce the amount of Sinemet by adding the Mirapex . I think the important question is how much trust do you have in your neurologist? Does he encourage you to do your own research? Is he supportive and encourage you to get second and third opinions? Are you confortable talking to him/her? Is your husband? Cathy William Heitman wrote: > In a message dated 10/15/99 8:34:12 AM Central Daylight Time, > [log in to unmask] writes: > > <<the medication regimen that works for one person might not work for all. >> > > Amen to that. Living with Sinemet is an "ART FORM." It is at once the > greatest and the worst weapon in our arsenal for daily living. > > Some do better than others. In general, take as little as possible to get > the needed effects. To that end, consider the agonists, amantadine, etc. to > be secondary or helper drugs. Learn to tolerate some off time. Good luck > helps. > > Good luck to you. > > WHH 56/38/37