I did cut to 1200 mg l0/100 tabs of Sinemet, & the doc is now very slowing adding Mirapex, hoping to decrease Sinemet even more. Would people on the list tell me of your experiences with Mirapex? I understand it has just been OK's as an antidepressant. Is that correct? Dawn William Heitman wrote: > In a message dated 10/18/99 6:35:19 PM Central Daylight Time, > [log in to unmask] writes: > > << . I was diagnosed in 1993, mainly have the > rigidity-type of PD. I was taking 1-1/2 Sinemet regular l0/100 every > 1-1/2 hours for a total of l850 mg/day. I did wonderfully well on this > for many months, until I got major dyskenesias. Even with these, my > energy & mood were terrific. I suppose I was over-medicated. >> > > It varies with the individual of course but 1850 mg per day is too much > L-dopa for almost anybody at any stage. Check out my "primer." Get that new > doctor's opinion and start tapering. Shoot at using about half that amount. > You will have to accept a little (maybe even a lot -especially in he > beginning) off time. Expect it to be tough to do. However, at the rate you > are going, you will get bad side effects (including mental) soon if you > don't have them already . > > Regards, > WHH