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Dawn Mirapex is not an antidepressant it is a dopamine agonist meaning that it acts like dopamine. Mirapex can be useful in decreasing the amount of l-dopa required. If you require a n antidepressant then you should be taking one although the depression might be either the result of or secondary to the PD. Charlie ----- Original Message ----- From: M. Dawn Legan <[log in to unmask]> To: <[log in to unmask]> Sent: Thursday, October 21, 1999 8:39 PM Subject: Re: Please Help! Meds > I did cut to 1200 mg l0/100 tabs of Sinemet, & the doc is now very slowing > adding Mirapex, hoping to decrease Sinemet even more. Would people on the list > tell me of your experiences with Mirapex? I understand it has just been OK's as > an antidepressant. Is that correct? > > Dawn > > William Heitman wrote: > > > In a message dated 10/18/99 6:35:19 PM Central Daylight Time, > > [log in to unmask] writes: > > > > << . I was diagnosed in 1993, mainly have the > > rigidity-type of PD. I was taking 1-1/2 Sinemet regular l0/100 every > > 1-1/2 hours for a total of l850 mg/day. I did wonderfully well on this > > for many months, until I got major dyskenesias. Even with these, my > > energy & mood were terrific. I suppose I was over-medicated. >> > > > > It varies with the individual of course but 1850 mg per day is too much > > L-dopa for almost anybody at any stage. Check out my "primer." Get that new > > doctor's opinion and start tapering. Shoot at using about half that amount. > > You will have to accept a little (maybe even a lot -especially in he > > beginning) off time. Expect it to be tough to do. However, at the rate you > > are going, you will get bad side effects (including mental) soon if you > > don't have them already . > > > > Regards, > > WHH