P&B Fahr <[log in to unmask]> wrote: Ivan, Isn't using 1/2 a Sinemet and 1/2 a CR equal to taking 1 Sinemet since breaking a Sinemet CR destroys its timed-release feature and it effectively becomes plain Sinemet? the statement that breaking CR Sinemet of either size into halves changes the slow dissolving is absolutely NOT true. read or download http://www.ridgecrest.ca.us/~rfvetter/levodopa.pdf Ron Vetter 1936, '84 PD dz mailto:[log in to unmask] http://www.ridgecrest.ca.us/~rfvetter