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I have been on mirapex since Dec 98. The first month i was on it, my hands swelled nightly to the point i thought the skin would burst. I do also get "sleep attacks", but have learned how to tell when they are coming on. I also take sinemet ct,4 times per day, and sinemet 6 times per day. With all 3, i get excellent control, but whenever i have tried to drop one, problems occur. i started on sinemet, and it worked for 4 hours, but off periods were really off, sinemet cr gave me a less complete control, but less drastic off and on periods. the mirapex i really did not think was doing much until i went off it for a week - without it, the senemet and sinemet cr lasts half as long. the hands quit swelling after 6 weeks or so, and as I've said, the sleep attacks still occur, but you can learn to recognize the signs and pull over. hope this helps someone bob ______________________________________________________ Get Your Private, Free Email at http://www.hotmail.com