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Tina, I'm on Amantadine, Sinemet and now recently he added Mirapex at night for restless leg syndrome. Since I've been on it, I rarely think about taking my Sinemet. It's miraculous for me! First time I was prescribed it, however, I ended up with edema (swollen ankles) so he took me off it. I realized later my dosage then was 1.5 mg twice a day (This was before I was on Sinemet.) and now I'm only on .25 mg. once a day (p.m.). So, reluctantly, due to the ankle swelling, I was taken off the Mirapex and went on Sinemet, but now I'm hopeful I can get off the Sinemet entirely and just increase the Mirapex dosage slightly. I see my neurologist about this tomorrow. (I am 60 by the way, so I don't know if my case is anything like your much earlier onset.) I've not had any problems falling asleep at the wheel, although at times I've gotten mighty drowsy on my way to work, but figured it was lack of caffeine which I'm also cutting out. Good luck, sometimes it takes a while for these drugs to do their work. Cheers, Brenda Tina wrote: > I am looking for any info on Mirapex side effects....The only side > effect I can find is about falling asleep. I am having bad joint pain > in my knees. Just started saturday, and I started my full dose of > Mirapex friday (1.5mg)day. I am also on Amantadine (generic for > Symmetrel). Still having tremors and balance problems, so far Mirapex > really hasnt helped me. I already have a call into my doctor, waiting > for return call. Just trying to get more info before I see the doctor. > He will not put me on sinemet because he says I am too young. He said > the longer you take it, the worse side effects you get down the road. > He said he only gives it to his older patients. My symptoms are tremor > in right hand, and head...balance problems, fallen 5 times in past 2 > weeks, joint pain in knees, right leg dragging and freezing (which has > caused most of falls), depression, fatigue, and trouble walking any > distance. I am only 31 yrs old. Any info would be greatly > appreciated. My doctor is really good, he and his team of doctors are > third in the nation in pallidomy surgeries. I really am just looking > for ideas or thoughts to bring up to my doctor when I go see him. > Thanks, and sorry for being so winded. > > Tina-----Fairfield, Ohio