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Sherry, I can only tell you of my experience...I was first prescribed 1.5 mg.
once a day p.m. for my parkinson's.  My immediate reaction was endema (swelling
in my ankles).  So, he took me off it and put me on Sinemet which
I had been avoiding.  I was already on Amantadine.  The sinemet was miraculous,
but am still only on 25 mg. 6 times a day.  I was taking two at a time 3 times a
day, but kept getting nauseated.  Then when I started having problems with
restless leg syndrome (lying down at night, my legs would tense up and jerk, I'd
relax them only to have it happen again and again.  Not good for trying to
sleep!)   So, he put me on .25 mg. TAB #XC at bedtime, and that has done the
trick!

But everyone's system works differently.  Just keep reading and asking questions
and keep your doc on his toes!

Cheers,

Brenda


Sherry Macredes wrote:

> Hi Guys,
>
> Well this is it, my first visit back to the neuro since diagnosis in August.
> I have been taking Mirapex and gradually adding more until now taking 3mg per
> day.  So far I haven't seen any results, just minor side effects.  On Tuesday
> I will see the neuro and I know already he will suggest taking off the
> Mirapex.  I hate to give up so soon after just getting to a dose that may
> help.  My symptoms are rigid muscles, loss of use of left hand (when I try to
> use it too much it shakes a lot) and dragging the left leg has just started.
> Of course there are the usual fatigue, insomnia etc that almost everyone on
> the list has mentioned.  What should I ask the neuro?  Any questions that I
> should ask that I'm not aware of?  What do you think about adding something
> to the Mirapex instead of just switching to something else, seems like
> everyone on the list is taking multiple drugs?  I don't know how informed my
> neuro is about PD how can I find out?  I have HMO insurance and don't know if
> I can switch or just arm myself with information and keep him on his toes.
> Any suggestions would be helpful to a newbie...
>
> Thanks
> Sherry