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In a message dated 11/12/1999 8:36:38 PM Central Standard Time, [log in to unmask] writes: << I have never heard of trunkeal dystonia, .nor of the concept that sinimet causes dystonia (in fact, this is somewhat confusing to me, in view of the fact that the dystonia which I have had in my shoulder for the last 2 years is relieved. by sinemet). >> Marty - Sinemet definitely causes dystonia in some people. Dick's primary side effect from Sinemet was dystonia, not dyskinesia, and it occurred at a very low dose. That was one of the things that made him a candidate for DBS. It's not uncommon for PWP to lean to one side or another. I don't know if you'll find anything in the archives about this, but there have been several discussions about it in the past. I've never heard of replacing Sinemet with Klonopin, and would think twice about agreeing to that. Klonopin won't replace any dopamine in your system. I'd think you'd be better off adding Mirapex or Requip or another agonist. You should then be able to reduce your dose of Sinemet. When Dick added Mirapex, he cut his Sinemet in half, and got rid of most of the mild dystonia that remained after his surgeries. Margie Swindler cg for Dick, 55/18