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Cari, Is he taking 1/4 of a 25-100 or (25 mg of levodopa) or 1 25-100 tablet which is 100 mg l-dopa? The 25-100 tablets contain 25mg carbidopa and 100 mg l-dopa . The speed of absoption of l-dopa from the gut is variable and depends on such factors as food present, gut motility, and other factors Also crossing the blood brain barrier also effects symptoms and that is effected by protein intake. So you see the setting of a schedule that will be predictive is almost impossible- although some people claim to be able to do it. What is the frequency that he takes his Sinemet at this point and how long has he had PD and taken Sinemet? Charlie ----- Original Message ----- From: Cari Barrett <[log in to unmask]> To: <[log in to unmask]> Sent: Monday, November 15, 1999 11:12 AM Subject: MED QUESTION > 1. today's IS a better day, thanks - sort of! > > 2. last week, in an effort to fine-tune my dad's med/sched and symptoms > (sinemet/dysk related), i received some feedback from one member (thanks!) > who graphed out the peaks and valleys based on daddy's schedule - it came > back mostly valleys - which is okay because it can be improved upon - > > 3. IS there a way (or ways) to plot out what the doses "should" do based on > a schedule? (or the layman's description of ".25 mg of sinemet 25-100 will > begin their effect in X minutes, peaking at X and slowing down in X" kind of > thing? > > if so, point me there! > > 4. what "graphing" program might you use? > > thanks - > cari