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All I know Ann is that my doctor took me off of it after I reported the swollen ankles! I'd be checking with your doctor! Cheers, Brenda Ann Gibbons wrote: > My husband has been taking Amantadine for about six months and has swollen feet and ankles. His hands are pretty swollen too. I know one of the side effects of Amantadine is swelling. Would this be a reason to stop taking it? What are the consequences of this swelling? > > Ann Gibbons cg Joe 65/2.5