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I don't know of a good reason beside discomfort...but am sure there is one! I even tried looking up edema in my Kaiser Permanente Healthwise book but nothing in the index, so guess it isn't too serious! Cheers, Brenda 50/1.5 Ann Gibbons wrote: > Thanks to all on the list who replied to my question about Amantadine and swelling. Good answers. However, I still don't know why that symptom might be considered "undesirable". Can somebody enlighten me? > > Ann Gibbons cg Joe 65/2.5