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On 27 Nov 99 at 15:28, Mario A. Gonzalez wrote: > Can someone explain why a person takes mirapex, tasmar, permax, etc., in addition > to Sinemet? > Be as verbose as you want. > thank you, > Mario A. Gonzalez [log in to unmask] Well Mario, I'll comment on one example... sinemet and tasmar. The sinemet acts to relieve the symptoms of Parkinsons by replacing some of the chemical missing in the Parkinsonian brain - dopamine. Tasmar is an adjunct medication that allows the best use of the sinemet - more dopamine actually reaches the brain. So this combination potentially allows you to reduce the sinemet or to increase the time between dosages or possibly both. Tasmar by itself is probably of little value. For me, Tasmar and sinemet meant no noticeable peak on time and no noticeable off time. Sinemet by itself is much more of a roller coaster. The basic premise of most long term meds is to obtain the best quality of life over the long haul with the least amount of drugs. It's a compromise of course. What works well for one may not work for another. We are all individuals and our medications have to be tailored to our individualities. Please consult your medical professional before contemplating any drug combinations. There may be serious interactions or side effects. I hope this simplistic example helps ....... murray [log in to unmask]