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Rats running mazes may help cure Parkinson's 

WebPosted Fri Nov 26 00:02:44 1999 
http://cbc.ca/cgi-bin/templates/view.cgi?/news/1999/11/25/Parkinsons991125

WASHINGTON - American scientists discovered a pattern in neuron firing 
when humans acquire a new habit. This pattern may help researchers find 
a treatment for Parkinson's disease. 

The study appears in Friday's Science magazine. 

By placing sensors on the striatum, the portion of the brain that is in 
charge of Parkinson's disease, researchers from the Massachusetts 
Institute of Technology were able to observe the rate of neural activity 
in rats' brains. 

The sensors detected a flurry of neural activity when the rats learned 
how to find a treat by travelling through a T-shaped maze. The computer 
recorded a visible pattern in the portion of the brain that learns new 
activities and habits. 

The scientists on the team hope that by pinpointing where the neurons 
break down, they can control Parkinson's through therapies or 
medication. 

Parkinson's disease is a degenerative neurological disorder that 
destroys brain cells that produce a chemical important for movement. 
Symptoms include muscle stiffening, tremors and difficulty moving. 

Link:

•Science Magazine

http://www.sciencemag.org/

•MIT department of Brain and Cognitive Sciences

http://web-bcs.mit.edu/


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