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To Michael Kamensky; That on the surface makes sense except for the fact that a large amount of dopamine metabolites are made in the body in different areas than the substantia nigra and therefore the metabolites I believe are unable to be separated from the metabolites of dopamine from other sources. fwiw Charlie ----- Original Message ----- From: Michael Kamensky <[log in to unmask]> To: <[log in to unmask]> Sent: Monday, November 29, 1999 10:34 PM Subject: Re: Stress and PD > >From: "(Martha Rohrer)" <[log in to unmask]> > > > The physiological > > parameters measured were > > urinary excretion rates of noradrenaline (NA), adrenaline (A), dopamine and > > cortisol (snip) Urinary excretion rates of noradrenaline and dopamine, blood > > pressure and heart rate > > were unchanged by the stressor. > > > This raises a question for me. I've always read that PD can't be measured > with lab tests, but I had never known that dopamine *can* be measured in > urine. Wouldn't a progressive depletion of dopamine in the body be reflected > in urine tests over time?