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Tasmar, Mirapex and Permax are all drugs under the classification of agonist. These drugs, very simply put, stimulate the cells that receive dopamine, making them more sensitive to the limited amounts of DA available in the brain. This allows most patients to take less Sinemet than they otherwise would taking Sinemet alone. Sincerely, Jeanne Lee-Rosner Associate Director of Education Parkinson's Disease Foundation ----- Original Message ----- From: Mario A. Gonzalez To: [log in to unmask] Sent: Saturday, November 27, 1999 5:28 PM Subject: Medication confused Can someone explain why a person takes mirapex, tasmar, permax, etc., in addition to Sinemet? Be as verbose as you want. thank you, Mario A. Gonzalez [log in to unmask]