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On 5 Dec 99 at 21:06, J. R. Bruman wrote: > Jenni Ayers wrote: > > > > Can you describe dystonia in 25< words? My husband takes Sinemet > > too . > > Dystonia, of the kind experienced in PD, is the uncontrolled cramping > of one or more muscles (not always the same ones), usually I think in > the legs, which can be quite painful. In athletics a similar cramp is > called a "charley horse". The PD dystonia is caused by depletion of > dopamine (or its effect) at the end of the dosage interval, and should > vanish shortly after taking the next scheduled medication dose. > Cheers, Joe > Good description Joe! I would like to add 1 comment... in my case I experienced dystonia at least 4 years before dx and at least 6 years before I took any sinemet... So, in my case, the dystonia is definitely not caused by sinemet. As Joe says, I experience dystonia when I'm off meds, and my dystonia is relieved by sinemet. I'm not on any other meds at this time... Cheers, ................. murray 55 now/ 49 dx/ 38 symptoms/ [log in to unmask]