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Ralph, I have been taking this drug for 66 months. I found no serious side effects. It will reduce the amount of ldopa [Sinemet or Atamet] which would be otherwise needed. Will Johnnston A.P.D.A. DelMarVA Chapter Pres. 4049 Oakland School Road Salisbury MD 21804 USA 410-543-0110 ---------- From: Ralph Reichert <[log in to unmask]> To: [log in to unmask] Subject: COMTRTAN (ENTACAPONE) seeking advice Date: Sunday, December 05, 1999 8:41 PM Edith is about to start COMTRAN (in addition to Atamet 25/100 5 times daily), for worstening tremor. Has anyone tried this drug? Anything to watch out for? Any helpful advice? Many thanks. Ralph.