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thank you diagnosed early 95. started sinemet late 96 with 3/day. mirapex made me sleep too much, even had one driving close call. i've forgotten the trouble with eldepryl took it twice, will look it up. i know first time i just felt hyper and not myself. maybe prescribed too early. i'm not taking vitamins --thought they interfered with sinemet absorption. and does sinemet interfere with my synthroid? thought i read that in package insert. I APPRECIATE YOUR HELP