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Bill,
 First thing is to get diagnosed by a movement disorder specialist.  If you haven't been diagnosed as having PD then why are you taking sinemet?  Work with your Dr.  to find the right med mix that's best for you.  You don't have to treat yourself.  PD meds have all kinds of potential side effects.  If you're not careful you could easily run into serious problems.  Been there, done that, and I was under Drs. care.  Can't imagine what would have happened if I was treating myself.  If you're having "wearing off" dystonia, like I get, then you probably need more sinemet  I take two 25/100 CR at bedtime and that seems to help.  Also, if I wake up during the night I'll take a regular 25/100 or two to avoid morning cramps.
Everybody's different.
 
Greg
47/35