hi all below is a summary listing of medical article citations which contain references to Parkinson's disease and which have been added to the PubMed WWWeb site in the past 30 days at: <http://www.ncbi.nlm.nih.gov/PubMed/> entering the PMID number in the search window there will take you to an abstract [synopsis] of the article [if one is available on-line] in any case, the full articles are accessible directly from the relevant medical journal maybe on the web [at a cost] or at a good library [at no cost] or maybe even at your own neurologist's office! EDUCATION + TITRATION R US janet ------------------------------------------------------------------------ Bezard E, et al. Effect of the alpha 2 adrenoreceptor antagonist, idazoxan, on motor disabilities in MPTP-treated monkey. Prog Neuropsychopharmacol Biol Psychiatry. 1999 Oct;23(7):1237-46. PMID: 10581645; UI: 20048346. Stack E, et al. Fall events described by people with Parkinson's disease: implications for clinical interviewing and the research agenda. Physiother Res Int. 1999;4(3):190-200. PMID: 10581625; UI: 20048326. Taylor CA, et al. Environmental, medical, and family history risk factors for Parkinson's disease: A New England-based case control study. Am J Med Genet. 1999 Dec 15;88(6):742-749. PMID: 10581500. Schraen-Maschke S, et al. Analysis of ERDA1, CTG18.1, and uncloned CAG/CTG repeat sequences in familial Parkinson's disease with anticipation. Am J Med Genet. 1999 Dec 15;88(6):738-741. PMID: 10581499. Kuhn DM, et al. L-DOPA-quinone inactivates tryptophan hydroxylase and converts the enzyme to a redox-cycling quinoprotein. Brain Res Mol Brain Res. 1999 Nov 10;73(1-2):78-84. PMID: 10581400. Schmidt J, et al. Regulation of heme oxygenase-1 expression by dopamine in cultured C6 glioma and primary astrocytes. Brain Res Mol Brain Res. 1999 Nov 10;73(1-2):50-59. PMID: 10581397. Gerschlager W, et al. Bilateral subthalamic nucleus stimulation improves frontal cortex function in Parkinson's disease: An electrophysiological study of the contingent negative variation. Brain. 1999 Dec;122(12):2365-2373. PMID: 10581229. York MK, et al. Neuropsychological outcome following unilateral pallidotomy. Brain. 1999 Dec;122(12):2209-2220. PMID: 10581217. Liberatore GT, et al. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. Nat Med. 1999 Dec;5(12):1403-1409. PMID: 10581083. Grunewald T, et al. NOS knockouts and neuroprotection. Nat Med. 1999 Dec;5(12):1354-1355. PMID: 10581072. Linda H, et al. Expression of MHC class I heavy chain and beta2-microglobulin in rat brainstem motoneurons and nigral dopaminergic neurons. J Neuroimmunol. 1999 Nov 1;101(1):76-86. PMID: 10580816; UI: 20046783. Mizruchin A, et al. Comparison of the effects of dopaminergic and serotonergic activity in the CNS on the activity of the immune system. J Neuroimmunol. 1999 Nov 15;101(2):201-4. PMID: 10580803; UI: 20046770. Aguirre JA, et al. A stereological study on the neuroprotective actions of acute modafinil treatment on MPTP induced nigral lesions of the male black mouse. Neurosci Lett. 1999 Nov 19;275(3):215-8. PMID: 10580713; UI: 20046680. Kodama Y, et al. Auditory brainstem responses in patients with autonomic failure with Parkinson's disease and multiple system atrophy. J Auton Nerv Syst. 1999 Sep 24;77(2-3):184-9. PMID: 10580301; UI: 20046246. Huebscher KJ, et al. Protein isoaspartyl methyltransferase protects from Bax-induced apoptosis. Gene. 1999 Nov 29;240(2):333-341. PMID: 10580153. Cenci MA, et al. Changes in the regional and compartmental distribution of FosB- and JunB-like immunoreactivity induced in the dopamine-denervated rat striatum by acute or chronic L-dopa treatment. Neuroscience. 1999;94(2):515-27. PMID: 10579213; UI: 20043814. Tarazi F, et al. Dopamine D4 receptors: significance for molecular psychiatry at the millennium. Mol Psychiatry. 1999 Nov;4(6):529-538. PMID: 10578234. Schulze J, et al. Clindamycin and nicotinic neuromuscular transmission. Lancet. 1999 Nov 20;354(9192):1792-3. PMID: 10577648; UI: 20043580. Kraft E, et al. Visual hallucinations, white matter lesions and disease severity in Parkinson's disease. Acta Neurol Scand. 1999 Jun;99(6):362-7. PMID: 10577270; UI: 99314579. Helmuth L. Fetal cells help Parkinson's patients. Science. 1999 Oct 29;286(5441):886-7. No abstract available. PMID: 10577234; UI: 20041510. Baggott M, et al. More about parkinsonism after taking ecstasy. N Engl J Med. 1999 Oct 28;341(18):1400-1. No abstract available. PMID: 10577097; UI: 99450931. Mazzoni P, et al. The freezing of time as a presenting symptom of Parkinson's disease. N Engl J Med. 1999 Oct 21;341(17):1317-8. No abstract available. PMID: 10577086; UI: 99442293. Bhatia KP, et al. Botulinum toxin is a useful treatment in excessive drooling in saliva. J Neurol Neurosurg Psychiatry. 1999 Nov;67(5):697. No abstract available. PMID: 10577041; UI: 20035692. Seibyl JP. Single-photon emission computed tomography of the dopamine transporter in parkinsonism. J Neuroimaging. 1999 Oct;9(4):223-8. PMID: 10540602; UI: 20008107. Zakzanis KK, et al. A neuropsychological comparison of demented and nondemented patients with Parkinson's disease. Appl Neuropsychol. 1999;6(3):129-46. PMID: 10497689; UI: 99427339. Kienzl E, et al. Iron as catalyst for oxidative stress in the pathogenesis of Parkinson's disease? Life Sci. 1999;65(18-19):1973-6. PMID: 10576448; UI: 20041867. Beuter A, et al. Using frequency domain characteristics to discriminate physiologic and parkinsonian tremors. J Clin Neurophysiol. 1999 Sep;16(5):484-94. PMID: 10576231; UI: 20041650. Pennathur S, et al. Mass Spectrometric Quantification of 3-Nitrotyrosine, ortho-Tyrosine, and o,o'-Dityrosine in Brain Tissue of MPTP treated Mice, a Model of Oxidative Stress in Parkinson's Disease. J Biol Chem. 1999 Dec 3;274(49):34621-34628. PMID: 10574926. Cutillas B, et al. Caspase inhibition protects nigral neurons against 6-OHDA-induced retrograde degeneration. Neuroreport. 1999 Aug 20;10(12):2605-8. PMID: 10574377; UI: 20039534. Pierantozzi M, et al. The effect of deep brain stimulation on the frontal N30 component of somatosensory evoked potentials in advanced Parkinson's disease patients. Clin Neurophysiol. 1999 Oct;110(10):1700-7. PMID: 10574285; UI: 20039442. Sabate M, et al. Vitiligo associated with tolcapone and levodopa in a patient with Parkinson's disease. Ann Pharmacother. 1999 Nov;33(11):1228-9. No abstract available. PMID: 10573327; UI: 20037998. Frank W, et al. Low dose cabergoline induced interstitial pneumonitis. Eur Respir J. 1999 Oct;14(4):968-70. PMID: 10573251; UI: 20037922. Rudolf J, et al. Deterioration of parkinsonian symptoms following treatment of dopaminergic hallucinosis with olanzapine. Eur Psychiatry. 1999 Oct;14(6):356-7. PMID: 10572371; UI: 20048779. Berger HJ, et al. Relationship between Memory Strategies and Motor Symptoms in Parkinson's Disease. J Clin Exp Neuropsychol. 1999 Oct;21(5):677-684. PMID: 10572286. Martinez-Martin P, et al. Conversion to controlled-release levodopa/carbidopa treatment and quality of life as measured by the Nottingham Health Profile. The Star Study Group. Neurologia. 1999 Aug-Sep;14(7):338-43. PMID: 10570620; UI: 20037198. Tsui JK, et al. Occupational risk factors in Parkinson's disease. Can J Public Health. 1999 Sep-Oct;90(5):334-7. PMID: 10570579; UI: 20037157. Piccini P, et al. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nat Neurosci. 1999 Dec;2(12):1137-1140. PMID: 10570493. Barker RA, et al. Functional integration of neural grafts in Parkinson's disease. Nat Neurosci. 1999 Dec;2(12):1047-1048. PMID: 10570477. de Bie RM, et al. Unilateral pallidotomy in Parkinson's disease: a randomised, single-blind, multicentre trial. Lancet. 1999 Nov 13;354(9191):1665-9. PMID: 10568567; UI: 20033215. Quinn N. Progress in functional neurosurgery for Parkinson's disease. Lancet. 1999 Nov 13;354(9191):1658-9. No abstract available. PMID: 10568561; UI: 20033209. Ilic TV, et al. Oxidative stress indicators are elevated in de novo Parkinson's disease patients. Funct Neurol. 1999 Jul-Sep;14(3):141-7. PMID: 10568214; UI: 20034209. Lin J, et al. Absence of G209A and G88C Mutations in the Alpha-Synuclein Gene of Parkinson's Disease in a Chinese Population. Eur Neurol. 1999 Nov;42(4):217-220. PMID: 10567818. Hutchinson M, et al. Parkinson's disease: a novel MRI method for determining structural changes in the substantia nigra. J Neurol Neurosurg Psychiatry. 1999 Dec;67(6):815-818. PMID: 10567508. Sakatani K, et al. Changes in cerebral blood oxygenation of the frontal lobe induced by direct electrical stimulation of thalamus and globus pallidus: a near infrared spectroscopy study. J Neurol Neurosurg Psychiatry. 1999 Dec;67(6):769-773. PMID: 10567495. Rinne JO, et al. Usefulness of a dopamine transporter PET ligand [(18)F]beta-CFT in assessing disability in Parkinson's disease. J Neurol Neurosurg Psychiatry. 1999 Dec;67(6):737-741. PMID: 10567489. Micek ST, et al. Tolcapone: a novel approach to Parkinson's disease. Am J Health Syst Pharm. 1999 Nov 1;56(21):2195-205. PMID: 10565698; UI: 20029428. Dunnett SB. Repair of the damaged brain. The alfred meyer memorial lecture 1998. Neuropathol Appl Neurobiol. 1999 Oct;25(5):351-62. PMID: 10564524; UI: 20032058. Meredith GE, et al. Immunocytochemical characterization of catecholaminergic neurons in the rat striatum following dopamine-depleting lesions. Eur J Neurosci. 1999 Oct;11(10):3585-96. PMID: 10564366; UI: 20032211. Jaber M, et al. Differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter. Eur J Neurosci. 1999 Oct;11(10):3499-511. PMID: 10564358; UI: 20032203. Maraganore DM, et al. Case-control study of the ubiquitin carboxy-terminal hydrolase L1 gene in Parkinson's disease. Neurology. 1999 Nov 10;53(8):1858-60. PMID: 10563640; UI: 20025164. [No authors listed] Developments in the treatment of Parkinson's disease. Drug Ther Bull. 1999 May;37(5):36-40. PMID: 10563057; UI: 20028797. Phillips NJ, et al. Validity of mortality data for Parkinson's disease. J Epidemiol Community Health. 1999 Sep;53(9):587-8. No abstract available. PMID: 10562888; UI: 20028628. Iansek R. Key points in the management of Parkinson's disease. Aust Fam Physician. 1999 Sep;28(9):897-901. PMID: 10561888; UI: 20024531. Ihara Y, et al. Hydroxyl radical and superoxide dismutase in blood of patients with Parkinson's disease: relationship to clinical data. J Neurol Sci. 1999 Nov 30;170(2):90-95. PMID: 10561523. Bennett JP. Free radicals, oxidative stress and the origin of Parkinson's disease. J Neurol Sci. 1999 Nov 30;170(2):75-76. No abstract available. PMID: 10561521. Galvin JE, et al. Axon pathology in Parkinson's disease and lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein. Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13450-5. PMID: 10557341; UI: 20027568. Scheife RT. Successful orchestration of antiparkinsonian pharmacotherapy. Pharmacotherapy. 1999 Nov;19(11 Pt 2):180S-186S. PMID: 10555946; UI: 20022872. Luer MS. Interventions to achieve tonic exposure to levodopa: delaying or preventing the onset of motor complications. Pharmacotherapy. 1999 Nov;19(11 Pt 2):169S-179S. PMID: 10555945; UI: 20022871. Gottwald MD. Maximizing the benefit: risk ratio of levodopa therapy in Parkinson's disease. Pharmacotherapy. 1999 Nov;19(11 Pt 2):162S-168S. PMID: 10555944; UI: 20022870. Lapane KL, et al. Prevalence, clinical characteristics, and pharmacologic treatment of Parkinson's disease in residents in long-term care facilities. SAGE Study Group. Pharmacotherapy. 1999 Nov;19(11):1321-7. PMID: 10555938; UI: 20022864. Schulz JB, et al. Molecular pathogenesis of movement disorders: are protein aggregates a common link in neuronal degeneration? Curr Opin Neurol. 1999 Aug;12(4):433-9. PMID: 10555832; UI: 20022758. Spacey SD, et al. The genetics of Parkinson's disease. Curr Opin Neurol. 1999 Aug;12(4):427-32. PMID: 10555831; UI: 20022757. Krack P, et al. Surgical treatment of Parkinson's disease. Curr Opin Neurol. 1999 Aug;12(4):417-25. PMID: 10555830; UI: 20022756. Poewe W. Recent advances in the drug treatment of Parkinson's disease. Curr Opin Neurol. 1999 Aug;12(4):411-5. No abstract available. PMID: 10555829; UI: 20022755. Metman LV, et al. Amantadine for levodopa-induced dyskinesias: a 1-year follow-up study. Arch Neurol. 1999 Nov;56(11):1383-6. PMID: 10555659; UI: 20022585. Melnick ME, et al. Effect of pallidotomy on postural control and motor function in Parkinson disease. Arch Neurol. 1999 Nov;56(11):1361-5. PMID: 10555656; UI: 20022582. Murer MG, et al. Levodopa in Parkinson's disease: neurotoxicity issue laid to rest? Drug Saf. 1999 Nov;21(5):339-52. PMID: 10554050; UI: 20019478. Papa SM, et al. Internal globus pallidus discharge is nearly suppressed during levodopa-induced dyskinesias. Ann Neurol. 1999 Nov;46(5):732-8. PMID: 10553990; UI: 20019418. Ouchi Y, et al. Presynaptic and postsynaptic dopaminergic binding densities in the nigrostriatal and mesocortical systems in early Parkinson's disease: a double-tracer positron emission tomography study. Ann Neurol. 1999 Nov;46(5):723-31. PMID: 10553989; UI: 20019417. ------------------------------------------------------------------------ janet paterson 52 now / 41 dx / 37 onset http://www.geocities.com/SoHo/Village/6263/ 613 256 8340 po box 171 almonte ontario canada k0a 1a0