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Phil, Funny you should bring this up. I'm on Requip only and was thinking 'bout asking the doc to add sinemet. But after reading all the post this now I'm not sure what to do. From what ''I've read my dose of 15mg daily is on the high side and it's still not taking care of every thing. The main thing it does is kick me in the butt as far as having any energy. I'm still getting the nap attacks ( sudden exhaustion ) When I talked to my doc this week he mentioned Comtran,what's the skinny on this, another $2.00 or $3.00 a piece pill that has a thousand side effects. You'll have to excuse me I'm a little pissed off this week with all this. Has anybody else found the more you read and learn the depressed you get. JIM ( no armor this week sirjames )