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----- Original Message ----- From: Ivan M Suzman <[log in to unmask]> To: <[log in to unmask]> Sent: Thursday, December 09, 1999 11:53 AM Subject: a revolutionary replacement for Sinemet > ^^^^^^ WARM GREETINGS FROM ^^^^^^^^^^^^ :-) > Ivan Suzman 50/39/36 [log in to unmask] :-) > Portland, Maine land of lighthouses 36 deg. F :-) > ******************************************************************** > Dear PIEnetters, > > Does anyone wish that you had to wait only 15 minutes, instead of 30-45 > minutes, for each dose of Sinemet to "kick in"? > > Imagine how your life might be if the dour, dreaded "off-periods" were > reduced to > a quick ten or fifteen minutes. Imagine the impact on work, travel and > family life! > > If Dupont or any smart competitor would make a totally new Sinemet, that > is quickly "dispersible" in water, like Madopar, as described below by > Nigel.Harland, I would be first in line for such a product! > > How do we find the FASTEST solution to manufacturing it? > We could alleviate a tremendous amount of suffering among us. > > Ivan > :-) > > On Fri, 3 Dec 1999 08:30:19 -0000 Nigel Harland <[log in to unmask]> > writes: > Dispersible means that the tablets > >will>dissolve in water, therefore making them available in liquid form. > > I am pleased to be able to say that the results of the changeover have > been all I could have hoped for, response times down to 15-20 minutes > without fail, kicking in quickly with minimal discomfort. The tablets > come in 125 mg and are scored so they can be cut, > > (CUT) > Hi Ivan:: I have been crushing my carbidopa/levodopa pills and suspending them in filtered water for several years at the advice of Dr. Bill Koller. I make up a suspension of 10 of the 25/100's in a liter. It has cut my response time down so that I can depend upon relief in about half an hour and I take smaller more frequent doses; every hour take 60 ml's.(2 oz.)PLease see our support groups web site for information on the dose bottle I use: It makes the frequent doses easy to measure THe URL is www.cjnetworks.com/~nekpa