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Mama's reaction to Comtan was a worsening of her dystonia but then she has had negative reactions with most PD medications. Many othe PWP's have had good reaction. Check out the Library webpage of NPF's website for info on Comtan. Teresa, Daughter of Mama (57/43/38) -----Original Message----- From: Parkinson's Information Exchange Network [mailto:[log in to unmask]]On Behalf Of Jennifer Siegel Sent: Thursday, December 09, 1999 4:27 PM To: [log in to unmask] Subject: Comtan Some of you have probably discussed this before, but I am new to the group. Today my neurologist prescribed Comtan for me to take with my sinemet. I haven't seen the package insert yet, but would be interested in knowing what your experience and knowledge is about Comtan. Thank you, Nancy Spires