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thanks for answering re comtan. my pharmacist had none and had to order it--$2/pill x 5/day in my case. i've only taken 4 or 5 doses but it does seem to help so far--definitely more movement, i guess dyskinesias but i call it 'writhing. anything is better than being off. for me, just increasing the sinemet didn't help. i was very depressed and taking a 6th sinemet just made me "dopey". i would like to keep in touch. i'm in maryland also--potomac--closer to d.c. i'm new to the listserve and have only "taken" but will be glad to contribute if i have anything of value. cheers. nancy spires