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Sir James, Paul & Greg: I think the jury is still out on the agonist only VS sinemet in early onset(before age 55). Since PD is the "designer" disease it is, ie effecting each patient uniquely, it will be up to the patient, the neurologist and interested observers to collaborate and try to come up with the best plan of treatment for each individual person who has Parkinson's. What works for Paul, Greg or Sir james may not work for Lady J. Lady J AKNA Jeanette Fuhr 49/47/44? and who is recuperating from Marathon Monday(a shopping experience at the outlet mall w/my sis B4 P day(Present day). Hope the smoke from our credit cards didn't cause anyone a problem! ---------- From: Greg Sterling <[log in to unmask]> To: [log in to unmask] Subject: Re: Sinemet will get you? Date: Tuesday, December 14, 1999 7:13 AM Paul, What exactly do you mean Sinemet will "get you"? Have you read the side effects on Requip? Greg 47/35/35 Paul Lauer wrote: >Sir James: >My words can't be construed as advice because I am not a medical professional >and can't lay claim to a wealth of experience because I am only coming to the >end of my first year with the disease. However, (there always seems to be >one), from everything I've read on this list and elsewhere, the better bet is >to to titrate away from Sinemet rather than toward it, so long as you can do >so without terribly affecting your quality of life. The idea being that for >most (and apparently not for all) , the Sinemet too will get you over time so >the longer the delay the longer it takes to get you. In the belief in this >knowledge (which has been confirmed by both - count 'em - my Neuros) I am >going in the other direction, increasing Requip and decreasing Sinemet. > >Regards, > >Paul H. Lauer >