Raj:
Being you mentioned Dr. Perlmutter, I was a patient of his during the winter
months that I spent in Florida.  He seemed to be very knowledgeable Dr.
three months ago I started on Glutathione here in Michigan.  I took the
intravenous injections twice a week for six weeks without a positive effect.
I guess I'm one of the unfortunate ones.
It sounds like your taking good care of yourself, by your regimen.  Keep up
the good work.

Ervin McCarthy
----- Original Message -----
From: "Brightline" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Tuesday, June 04, 2002 4:33 PM
Subject: Raj/glutathione


> Hi! Ervin & Rayilyn:
>     I have never tried Sinemet, eventhough I have a prescrition for it.  I
> am sure it will be of help, based on the nearly 30 years of experience
with
> levodopa.  However, I am still reluctant to try it due to its mile long
list
> of side effects, (however low freqnuency of occurrence they might be) and
am
> keeping it handy as a last resort.  I may not be surprised if for some
> people it does not work.  Even in the NPF info it states that L-dopa has
> been shown to be harmful to dopamine producing cells in vitro and in vivio
> in animal studies.  It states that L-dopa may or may not be beneficial!
> But, both Dr. AH Rajput and Dr. Jancovics believe, however, it is not
> harmful to humans.  This is supported by the fact that since the
> introduction of L-dopa or sinemet, people with PD have been living longer.
>     In the article by Dr. Perlmuter, it says that both dopmine and
> glutathione are low in PD patients.  For some reason L-dopa application
has
> caught up and the fate of glutatione deficiency has been left hanging in
the
> air.  I have been taking glutathione - reduced for the last week or so.  I
> definitely feel some improvement in my condition, good enough to postpone
> taking sinement.  I do not know how to quantitate my results. I am not
sure
> how long this beneficial effect will last.  I would like to know your
> experience with Glutathione.  One should not expect miracles, since
whatever
> is lost is lost for ever.  I only hope this will slow down the prgression
of
> PD, as evidencd by decrease in and not total elimnation of the symptoms of
> PD.
>
>     First thing in the morning I take a cup of greentea with a tablespoon
of
> honey with  no milk or sugar.   Some times I include about 25-50 mg of
> caffeine pill along with my tea.
>     I am taking glutathione along with phosphatydilserine, B6, B12,
Folate,
> Vitamin E and about 1/3 pill of multivitamain (senior edition with less
> amount of iron) every day in the morning just before breakfast.
>     My breakfast consists of bran flakes, about  12 fresh almonds, a pinch
> of peeled pumpkin seeds (for my prostate problems), and a spoon full of
> powdered flax seed; this also includes one cup of a fruit juice cocktail
> (1:1 mix of orange and tomato juices with a small amount of blue berry
> juice).
>     (I am a little bit uncertain about the benefit of blue berry or bb
juice
> for PD patients, since aluminum sulfate is used as a fertlizer for blue
> berry plants.  Aluminum has been implicated in PD and in Alzheimer's.
Does
> anybody know the aluminum content of blue berries? So do I with regard to
> commercial yogurts.  In 1960s and 70s,  the preservative in commercial
> yogurt called MSG or monosodium glutamate [also earlier used in  Chinese
> cooking] has been a contentious issue since in animal studies this caused
> serious nervous system disorders.  Some yogurt products still state 1-2%
MG
> on their stickers.  I often wonder is MG is the same as MSG!)  Sorry for
> being paranoid.  It is better to be careful, than feeling sorry later.
>
>     For lunch and supper, I take pretty much anything, except that I make
> sure to take a good dose of fresh vegetables and fruits.
>     Of course, I also include at least 20-30 min of exercise every
morning.
>
>     There is no guarantee that what might seem to work for me may work for
> everybody, since as you well know, PD is a personalized disease, often
with
> comomn symptoms that show up at variable rate and similarly, the resonse
to
> any drug is also variable between individals.  YOU SHOULD DEFINIELY
CONSULT
> WITH YOR DOCTOR ON ANYTHING YOU TAKE OR DO FOR YOUR PD.
>
> QUESTION:
>     If both dopamine and glutathione are low in PD patients, I would ask
> myself if it would make sense to take glutathione in addition to sinemet.
>     BUT, I DON'T HAVE THE ANSWER FOR THIS QUESTION.  SO PLEASE DO NOT TRY.
> SOME TIMES, THERE COULD BE UNFORSEEN HARMFUL EFFECTS IF TWO DRUGS ARE
> COMBINED.
>     GOOD EXAMPLE:  A CLINICAL TRIAL WAS STOPPED HALFWAY IN ENGLAND
RECENTLY
> SINCE IT INCREASED MORTALITY RATE AMONG THE GROUP OF PD PATIENTS THAT WERE
> GIVEN L-DOPA (SINEMET?) AND SELGELINE!
>
>
>     Raj
> [log in to unmask]
> ----- Original Message -----
> From: "Ervin McCarthy" <[log in to unmask]>
> To: <[log in to unmask]>
> Sent: Tuesday, June 04, 2002 9:33 PM
> Subject: Re: Raj/glutathione
>
>
> > Rayilyn, I have gotten the same results from Sinemet on three occasions.
> I
> > was curious if anyone else had the same results.  Now I know.  Thank
you.
> > Ervin McCarthy
> > ----- Original Message -----
> > From: "Rayilyn Brown" <[log in to unmask]>
> > To: <[log in to unmask]>
> > Sent: Monday, June 03, 2002 9:39 PM
> > Subject: Re: Raj/glutathione
> >
> >
> > > Raj,  Thanks for the info on glutathione...that it is a small
molecule.
> > I'm
> > > going to try the oral glutathione first, before intravenous.  Sinemet
> > never
> > > helped me much and after a year made dystonia in my feet unbearable.
> > I''ve
> > > tried it again 3 times with same result. Rayilyn
> > >
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