>I am in the process of reading the actual study for the recent CoQ10 test.
>Some interesting things so far:
>People were excluded from the study for the following reasons:
>1.  "The use of drugs known to interfere with mitochondrial activity."  I
>would like to avoid these all the time--how do we find out drugs on this
>list?
>
>2.  "The use of methylphenidate hydrochloride, cinnarizine, reserpine,
>amphetamines, or monoamine oxidase-A inhibitors within 6 months before the
>baseline visit."   I havent done my research yet to determine if this
>restriction is for positive or negative reasons i.e. could influence outcome
>of the subject patient in a positive or negative manner.
>
>3.  "An unstable dosage of drugs active in the central nervous system (e.g.
>anxiolytics, hypnotics, benzodiazepines, and anti-depressants) during the 60
>days before the baseline visit."   HOw would this impact the outcome of
>experiment?
>
>Another interesting point:  "The wafers with active study drug contained 300
>mg of coenzyme Q10 and 300 IU of vitamin E as a lipophilic carrier"
>Hmmmmm--i dont remember this coming up in the discussion earlier.  I dont
>think the Vitaline CoQ10 wafers contain any vitamin E!
>
>Also:  "Patients were asked to take a standard daily multivitamin without
>minerals but no other supplemental vitamins."
>
>And finally:  "A blood sample was again drawn at the final visit for
>evaluation of platelet mitochondrial function."  Could a simple blood test
>be used to help diagnose PD?
>
>Bob
>
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HELLO BOB: I SPOKE TO VITALINE  (1-800 287-5972).  CURRENT SUPPLY OF WAFERS
DON'T CONTAIN VIT E.  ON ABOUT NOV 15TH THEY'LL BE ADDING 300 IU OF E TO
EACH WAFER TO DUPLICATE THAT USED IN STUDY.   RALPH

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